Complement Factor B anticorps (Fragment Bb)

N° du produit ABIN317054

Détail du produit anti-Complement Factor B anticorps

Antigène: Complement Factor B (CFB)

Épitope: Fragment Bb

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Complement Factor B est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificité: This antibody recognises a neoantigen of the Bb fragment of complement factor B.

Attributs du produit: Synonyms: Properdin factor B, C3/C5 convertase, PBF2, CFB, BF, BFD, Glycine-rich beta glycoprotein

Purification: Purified IgG prepared by affinity chromatography on Protein A

Immunogène: Binds neoantigen of fragment Bb from human complement factor B.

Clone: 032B-22-1-X

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry. ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0mg/mL

Buffer: Borate buffered saline pH 8.2 - 8.4 containing 0.02 % Sodium Azide (NaN3)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

Date de péremption: 12 months

Détails sur Complement Factor B

Antigène: Complement Factor B (CFB)

Autre désignation: Complement Factor B (CFB Produits)

Synonymes: anticorps AHUS4, anticorps BF, anticorps BFD, anticorps CFAB, anticorps FB, anticorps FBI12, anticorps GBG, anticorps H2-Bf, anticorps PBF2, anticorps bf, anticorps Bf-1, anticorps Brre-Bf, anticorps zgc:114032, anticorps Bf, anticorps Sp152, anticorps bfb-A, anticorps Bf B, anticorps LOC397725, anticorps bf/c2, anticorps CFB, anticorps AI195813, anticorps AI255840, anticorps B, anticorps C2, anticorps Fb, anticorps Da1-24, anticorps complement factor B, anticorps complement factor B S homeolog, anticorps complement factor B L homeolog, anticorps CFB, anticorps cfb, anticorps bf, anticorps cfb.S, anticorps cfb.L, anticorps bf/c2, anticorps LOC100555981, anticorps Cfb

Sujet: Factor B is present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit) leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B

ID gène: 629

UniProt: P00751

Pathways: Système du Complément, Proton Transport, Ribonucleoside Biosynthetic Process