Cytochrome C anticorps
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- Antigène Voir toutes Cytochrome C (CYCS) Anticorps
- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
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Reactivité
- Humain, Rat, Souris, Lapin
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Cytochrome C est non-conjugé
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Application
- Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- Specificité
- This antiobdy recognises cytochrome c, originally termed Apaf-2, an evolutionarily conserved protein which acts as an essential mitochondrial electron carrier between respirable substrates and oxygen, during aerobic energy production. Clone 2G8 is reported to block the role of cytochrome c as a co-factor in the activation of caspase 9. Removal of sodium azide is recommended prior to use in functional assays
- Attributs du produit
- Synonyms: CYCS, CYC
- Purification
- Purified IgG prepared by affinity chromatography on Protein A
- Immunogène
- Human cytochrome c
- Clone
- 2G8
- Isotype
- IgG1
- Top Product
- Discover our top product CYCS Anticorps primaire
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- Indications d'application
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Flow Cytometry. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.09 % Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only. - Date de péremption
- 12 months
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- Antigène
- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
- Autre désignation
- Cytochrome C (CYCS Produits)
- Synonymes
- anticorps CYC, anticorps HCS, anticorps THC4, anticorps cyct, anticorps cyc, anticorps hcs, anticorps CYCS, anticorps cytc, anticorps CYCSA, anticorps CG17903, anticorps Cyt C, anticorps Cyt c, anticorps Cyt-c2, anticorps CytC-2, anticorps Cytc, anticorps Cytc-p, anticorps DC4, anticorps DMc01, anticorps Dmel\\CG17903, anticorps cyt c, anticorps cyt c-p, anticorps cyt-c-p, anticorps cyt-c2, anticorps cyt.c, anticorps cytochrome c, anticorps dc4, anticorps pDMc01, anticorps wu:fk52b01, anticorps zgc:86706, anticorps ENSMUSG00000058927, anticorps cytochrome c, somatic, anticorps cytochrome c, somatic S homeolog, anticorps Cytochrome c proximal, anticorps cytochrome c, somatic b, anticorps cytochrome c, somatic pseudogene, anticorps cytochrome c-like, anticorps cytochrome c, anticorps CYCS, anticorps cycs.S, anticorps cycs, anticorps Cycs, anticorps Cyt-c-p, anticorps cycsb, anticorps Gm10053, anticorps LOC100724240, anticorps CYC, anticorps LOC100847700, anticorps LOC101107954, anticorps LOC106829744, anticorps LOC106992390, anticorps LOC102085712
- Sujet
- A second major function for cytochrome c is its role as an intermediate in apoptosis, both through its association with inositol-3-phosphate receptor (IP3 receptor) which acts as an ER calcium release channel, and its association with apoptotic protease activating factor 1 (Apaf-1), resulting in the formation of the apoptosome protein complex which then recruits and activates pro-caspase 9 (Apaf-3).Synonyms: CYC, CYCS
- ID gène
- 54205
- UniProt
- P99999
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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