FZD1 anticorps
-
- Antigène Voir toutes FZD1 (Fzd1) Anticorps
- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp FZD1 est non-conjugé
-
Application
- Western Blotting (WB), Immunofluorescence (IF)
- Specificité
- This antibody detects endogenous levels of Frizzled-1 protein.(region surrounding Leu55)
- Purification
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product Fzd1 Anticorps primaire
-
-
- Indications d'application
-
ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Antigène
- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
- Autre désignation
- FZD1 / Frizzled-1 (Fzd1 Produits)
- Synonymes
- anticorps CG17697, anticorps CG3646, anticorps DFZ1, anticorps DFz, anticorps DFz1, anticorps Dfz1, anticorps Dm Fz1, anticorps Dmel\\CG17697, anticorps FZ, anticorps Frz, anticorps Fz, anticorps Fz1, anticorps frz, anticorps fz1, anticorps fz[[1]], anticorps Fz-1, anticorps cFz-1, anticorps Xfrizzled-1, anticorps frizzled1, anticorps frz-1, anticorps frz1, anticorps fzd1-A, anticorps AW227548, anticorps FZ-1, anticorps frizzled, anticorps frizzled class receptor 1, anticorps frizzled class receptor 1 L homeolog, anticorps fz, anticorps FZD1, anticorps Fzd1, anticorps fzd1.L
- Sujet
- The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several secreted mammalian frizzled-related proteins: FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3, FRP-4 and SARP3 (also designated FRP-5), have been identified. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt. The frizzled-1 gene maps to human chromosome 7q21 and is expressed in adult heart, placenta, lung, kidney, pancreas, prostate and ovary and in fetal lung and kidney. Frizzled-2 is expressed in adult heart and fetal brain, lung and kidney. The frizzled related proteins FRP-1, FRP-2, FRP-3, FRP-4 and SARP3 are secreted proteins of approximately 30 kDa that contain regions of homology to the cysteine-rich ligand-binding domain of frizzled and a conserved hydrophilic carboxy terminal.Synonyms: Fz-1, FzE1, hFz1
- Poids moléculaire
- approx. 71 kDa
- ID gène
- 8321
- NCBI Accession
- NP_003496
- UniProt
- Q9UP38
- Pathways
- Signalisation WNT, Asymmetric Protein Localization
-