HTR2C anticorps

N° du produit ABIN317726

Détail du produit anti-HTR2C anticorps

Antigène: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTR2C est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects endogenous levels of SR-2C protein.(region surrounding Gln437)

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1: 40000approx. 1: 60000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.3 with 0.05 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur HTR2C

Antigène: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Autre désignation: Serotonin Receptor 2C (HTR2C) (HTR2C Produits)

Synonymes: anticorps 5-HT2C, anticorps 5-HTR2C, anticorps HTR1C, anticorps 5-HT2cR, anticorps 5HT1c, anticorps Htr1c, anticorps SR1, anticorps 5HT-1C, anticorps 5HT2C, anticorps 5-HT-2C, anticorps 5-ht2cr, anticorps si:dkey-24g18.2, anticorps 5ht2c, anticorps 5HTR2C, anticorps 5-hydroxytryptamine receptor 2C, anticorps 5-hydroxytryptamine (serotonin) receptor 2C, anticorps 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled S homeolog, anticorps 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1, anticorps 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled, anticorps HTR2C, anticorps Htr2c, anticorps htr2c.S, anticorps htr2cl1, anticorps LOC407134

Sujet: The members of the G protein coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Members of the β-Arrestin family regulate receptor binding to G proteins. β-Arrestins have been found to be located at postsynaptic sites, where they are thought to act in concert with βARK (βARK1, also designated GRK 2, or βARK2, also designated GRK 3) to regulate G protein-coupled neurotransmitter receptors. Expression of β- Arrestin-1 and b-Arrestin-2 is seen predominantly in spleen and neuronal tissues. It has been shown that β-Arrestin-1 expression is modulated by intracellular cAMP, which may be a novel mechanism for the regulation of receptor- mediated responses.Synonyms: 5-HT-2C, 5-HT2C, 5-HTR2C, 5-hydroxytryptamine receptor 2C, 5HT-1C, HTR1C

Poids moléculaire: approx. 55 kDa

ID gène: 3358

NCBI Accession: NP_000859

UniProt: P28335

Pathways: Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour