FZD2 anticorps
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- Antigène Voir toutes FZD2 Anticorps
- FZD2 (Frizzled Family Receptor 2 (FZD2))
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FZD2 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Specificité
- This antibody detects endogenous levels of Frizzled-2 protein.(region surrounding Glu240)
- Purification
- Affinity Chromatography using epitope-specific immunogen
- Top Product
- Discover our top product FZD2 Anticorps primaire
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- Indications d'application
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- FZD2 (Frizzled Family Receptor 2 (FZD2))
- Autre désignation
- FZD2 / Frizzled-2 (FZD2 Produits)
- Synonymes
- anticorps BG01711, anticorps CG9739, anticorps D-Fz2, anticorps D-fz2, anticorps DFZ2, anticorps DFz-2, anticorps DFz2, anticorps Dfrz2, anticorps Dfz2, anticorps Dfz[[2]], anticorps Dm Fz2, anticorps Dmel\\CG9739, anticorps FZ2, anticorps Fz2, anticorps dFz2, anticorps dfz(2), anticorps dfz2, anticorps dfz2r, anticorps frz2, anticorps fz-2, anticorps fz8, anticorps zfz2, anticorps zg08, anticorps cb383, anticorps wu:fb70g09, anticorps FZD2, anticorps fzE2, anticorps hFz2, anticorps Fz-10, anticorps Fzd10, anticorps cFz-2, anticorps frizzled2, anticorps fz2, anticorps xfz2, anticorps AL033370, anticorps AW456835, anticorps Fz10, anticorps Mfz10, anticorps Mfz10a, anticorps frizzled 2, anticorps frizzled class receptor 2, anticorps frizzled class receptor 2 S homeolog, anticorps fz2, anticorps fzd2, anticorps FZD2, anticorps Fzd2, anticorps fzd2.S
- Sujet
- The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy-terminal Ser/Thr-XXX-Val motif. The proteins in this family function as receptors for Wnt and are generally coupled to G proteins. Frizzleds are members of the G protein-coupled receptor superfamily. Frizzled-2 is expressed in the fetal kidney and lung and in the adult ovary and colon. Frizzled-2 mediates the Wnt/cGMP/Ca2+ pathway. It binds Wnt proteins and signals by activating the release of stored calcium. Frizzled-2 expression is regulated by Angiotensin II. Activated frizzled-2 suppresses the activity of protein kinase G, and activates NFAT-dependent transcription, the phosphatidylinositol pathway and calcium sensitive enzymes.Synonyms: Fz-2, FzE2, hFz2
- Poids moléculaire
- approx. 55 kDa
- ID gène
- 2535
- NCBI Accession
- NP_001457
- UniProt
- Q14332
- Pathways
- Signalisation WNT
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