MBP anticorps

N° du produit ABIN318414

Détail du produit anti-MBP anticorps

Antigène: MBP (Myelin Basic Protein (MBP))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBP est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody is specific for myelin basic protein (MBP), an abundant protein component of the myelin membrane and is reported to have a role in its formation and stabilisation.

Purification: Purified IgG prepared by affinity chromatography on Protein G

Immunogène: Native Myelin Basic Protein from Human brain

Isotype: IgG

Information d'application

Indications d'application: Western Blot: detects band at 18.5 kDa on reducing SDS-PAGE against rat brain lysate. ELISA: 1/100 - 1/400.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % Sodium Azide (NaN3)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MBP

Antigène: MBP (Myelin Basic Protein (MBP))

Autre désignation: Myelin Basic Protein (MBP Produits)

Synonymes: anticorps C76307, anticorps Hmbpr, anticorps R75289, anticorps golli-mbp, anticorps mld, anticorps shi, anticorps Mbps, anticorps cb274, anticorps fj33b11, anticorps mbp, anticorps wu:fj33b11, anticorps wu:fq15b02, anticorps zgc:136630, anticorps MGC115135, anticorps myelin basic protein, anticorps myelin basic protein a, anticorps myelin basic protein L homeolog, anticorps MBP, anticorps Mbp, anticorps mbpa, anticorps mbp, anticorps mbp.L

Sujet: The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.Synonyms: MBP, Myelin membrane encephalitogenic protein

ID gène: 4155

NCBI Accession: NP_001020252

UniProt: P02686