Growth Hormone 1 anticorps

N° du produit ABIN318574

Cet anticorps Lapin Polyclonal détecte spécifiquement Growth Hormone 1 dans WB, IF, IHC (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain, Rat, Chien, Mouton et Cat.

Aperçu rapide pour Growth Hormone 1 anticorps (ABIN318574)

Antigène: Growth Hormone 1 (GH1)

Reactivité: Humain, Rat, Chien, Mouton, Cat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Growth Hormone 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Growth Hormone 1 anticorps

Specificité: This antibody recognizes human Growth Hormone (GH), which acts to control body growth and metabolic activity. In Western blotting a band of approximately 20 kDa is seen using lysates of human pituitary gland.

Purification: Purified IgG prepared by affinity chromatography on Protein G

Immunogène: Growth hormone from ovine pituitary.

Isotype: IgG

Information d'application

Indications d'application: Western blot: 1/50-1/500. Immunofluorescence: 1/10-1/100. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: 1/500-1/4000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 5.0 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Storage in frost-free freezers is not recommended.

Détails sur Growth Hormone 1

Antigène: Growth Hormone 1 (GH1)

Autre désignation: Somatotropin / Growth Hormone / GH1

Sujet: Human growth hormone (hGH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. The effects of hGH in the body can be generally described as anabolic. It stimulates amino acid uptake and protein synthesis in muscle and other tissues. Growth Hormone (GH1) is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Genes for growth hormone (GH) are found in a gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. The GHN1 gene is transcribed exclusively in the pituitary, whereas the other 4 genes are expressed only in placental tissues. Several isoforms of GH1 exist. Human growth hormone (hGH) is also used as a reporter protein, because it is secreted from mammalian cells it can be assayed by ELISA on culture supernatant using antibodies to determine the level of expression.Synonyms: Growth hormone 1, HGH, Pituitary growth hormone

ID gène: 2688

NCBI Accession: NP_000506

UniProt: P01241

Pathways: Signalisation NF-kappaB, Signalistation JAK/STAT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process