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IRF7 anticorps (Middle Region)

L’anticorps Lapin Polyclonal anti-IRF7 a été validé pour WB. Il convient pour détecter IRF7 dans des échantillons de Humain.
N° du produit ABIN318752

Aperçu rapide pour IRF7 anticorps (Middle Region) (ABIN318752)

Antigène

Voir toutes IRF7 Anticorps
IRF7 (Interferon Regulatory Factor 7 (IRF7))

Reactivité

  • 79
  • 57
  • 56
  • 17
  • 8
  • 3
  • 2
  • 2
  • 1
Humain

Hôte

  • 69
  • 11
Lapin

Clonalité

  • 57
  • 23
Polyclonal

Conjugué

  • 26
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Cet anticorp IRF7 est non-conjugé

Application

  • 51
  • 20
  • 20
  • 14
  • 14
  • 13
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)
  • Épitope

    • 16
    • 16
    • 15
    • 11
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Specificité

    This antibody detects Human Interferon Regulatory Factor 7 (IRF7). Other species not tested.

    Purification

    Affinity Chromatography

    Immunogène

    14 amino acid peptide sequence near the center of Human IRF7.

    Isotype

    IgG
  • Indications d'application

    Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 51 kDa in 293 whole celllysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS, 0.02 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    IRF7 (Interferon Regulatory Factor 7 (IRF7))

    Autre désignation

    IRF7

    Sujet

    IRF7 is a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production. Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.Synonyms: IRF-7, Interferon regulatory factor 7

    ID gène

    3665

    NCBI Accession

    NP_001563

    UniProt

    Q92985

    Pathways

    Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
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