IRF7 anticorps (Middle Region)
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- Antigène Voir toutes IRF7 Anticorps
- IRF7 (Interferon Regulatory Factor 7 (IRF7))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IRF7 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects Human Interferon Regulatory Factor 7 (IRF7). Other species not tested.
- Purification
- Affinity Chromatography
- Immunogène
- 14 amino acid peptide sequence near the center of Human IRF7.
- Isotype
- IgG
- Top Product
- Discover our top product IRF7 Anticorps primaire
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- Indications d'application
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Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 51 kDa in 293 whole celllysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, 0.02 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- IRF7 (Interferon Regulatory Factor 7 (IRF7))
- Autre désignation
- IRF7 (IRF7 Produits)
- Synonymes
- anticorps wu:fl24c03, anticorps zgc:66043, anticorps zgc:77947, anticorps IRF7, anticorps irf7, anticorps IRF-7H, anticorps IRF7A, anticorps IRF7B, anticorps IRF7C, anticorps IRF7H, anticorps interferon regulatory factor 7, anticorps irf7, anticorps IRF7, anticorps Irf7
- Sujet
- IRF7 is a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production. Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.Synonyms: IRF-7, Interferon regulatory factor 7
- ID gène
- 3665
- NCBI Accession
- NP_001563
- UniProt
- Q92985
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
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