IRF7 anticorps (C-Term)

N° du produit ABIN318755

Cet anticorps Lapin Polyclonal détecte spécifiquement IRF7 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour IRF7 anticorps (C-Term) (ABIN318755)

Antigène: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IRF7 anticorps

Épitope: C-Term

Specificité: This antibody detects an epitope within the C-terminal of Human Interferon Regulatory Factor 7 (IRF7).

Purification: Affinity Chromatography.

Immunogène: 14 amino acid peptide sequence near the carboxy terminus of Human IRF7.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1.0-2.0 μg/mL. This antibody detects a band of approximately 51 kDa in 293 whole cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IRF7

Antigène: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Autre désignation: IRF7

Sujet: IRF7 is a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production. Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.Synonyms: IRF-7, Interferon regulatory factor 7

ID gène: 3665

NCBI Accession: NP_001563

UniProt: Q92985

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy