MAP2K5 anticorps (pSer311, pThr315)

N° du produit ABIN318850

Détail du produit anti-MAP2K5 anticorps

Antigène: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Épitope: pSer311, pThr315

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poulet, Poisson zèbre (Danio rerio), Xenopus laevis, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2K5 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody specifically recognises 49 kDa MEK5, also known as MAP2K5, when phosphorylated at Ser311 and Thr315. Activation of MEK5 itself is regulated by upstream MAP3K3/MEKK3, and phosphorylation of MEK5 at both the Ser311 and Thr315 sites has been implicated in cell proliferation.

Purification: Purified

Immunogène: Synthetic phosphopeptide corresponding to an amino acid sequence within MEK5 , which includes phoshorylated Ser311 and Thr315.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1: 1000, detects a band of approximately 49 kDa in rat testes cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM Hepes pH 7.5 containing 0.09 % Sodium Azide (NaN3), 0.01 % Bovine Serum Albumin, 50 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MAP2K5

Antigène: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Autre désignation: MAP2K5 (MAP2K5 Produits)

Synonymes: anticorps Mek5, anticorps HsT17454, anticorps MAPKK5, anticorps MEK5, anticorps PRKMK5, anticorps AI324775, anticorps AI428457, anticorps Mapkk5, anticorps Prkmk5, anticorps fb73f02, anticorps wu:fb73f02, anticorps zgc:172137, anticorps ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5, anticorps ATMAP2K_ALPHA, anticorps ATMEK5, anticorps ATMKK5, anticorps MAP KINASE KINASE 5, anticorps MAP kinase kinase 5, anticorps MAP2K_A, anticorps mitogen activated protein kinase kinase 5, anticorps mitogen-activated protein kinase kinase 5, anticorps mitogen-activated protein kinase kinase 5 L homeolog, anticorps MAP kinase kinase 5, anticorps Map2k5, anticorps MAP2K5, anticorps map2k5, anticorps map2k5.L, anticorps MKK5

Sujet: MEK5 is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family, which acts as a key regulator in a mitogen-activated protein (MAP) kinase cascade, and hence growth factor-induced cellular stimulation. MEK5 exists in naturally occurring MEK5alpha and MEK5beta splice variants, the former of which is known to specifically activate/regulate MAPK7/ERK5/BMK1, whilst the latter may act as a suppressor of MAPK7 activation.Synonyms: Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MEK5, MKK5

ID gène: 5607

NCBI Accession: NP_001193733

UniProt: Q13163

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway