HDAC2 anticorps (pSer394)

N° du produit ABIN319237

Détail du produit anti-HDAC2 anticorps

Antigène: HDAC2 (Histone Deacetylase 2 (HDAC2))

Épitope: pSer394

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody HDAC2 (pSer394) detects endogenous levels of HDAC2 only when phosphorylated at Serine 394.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic phosphopeptide derived from human HDAC2 around the phosphorylation site of serine 394 (E-D-SP-G-D).

Information d'application

Indications d'application: Western blot (1/500-1/1000). Immunohistochemistry (1/50-1/100). Immunofluorescence (1/100-1/200).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at-20 °C.

Détails sur HDAC2

Antigène: HDAC2 (Histone Deacetylase 2 (HDAC2))

Autre désignation: HDAC2 (HDAC2 Produits)

Synonymes: anticorps HD2, anticorps RPD3, anticorps YAF1, anticorps D10Wsu179e, anticorps Yy1bp, anticorps mRPD3, anticorps HISTONE DEACETYLASE, anticorps T1N24.9, anticorps T1N24_9, anticorps histone deacetylase 2, anticorps histone deacetylase 2, anticorps histone deacetylase 2 S homeolog, anticorps HDAC2, anticorps Hdac2, anticorps hdac2.S, anticorps HDA2

Sujet: Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly conserved from yeast to human.Synonyms: HD2, Histone deacetylase 2

ID gène: 3066

NCBI Accession: NP_001518

UniProt: Q92769

Pathways: Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2