Tissue factor anticorps (FITC)
Aperçu rapide pour Tissue factor anticorps (FITC) (ABIN320295)
Antigène
Voir toutes Tissue factor (F3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Specificité
- This antibody recognises CD142. The CLB/TF-5 antibody has been used successfully in an ELISA assay as a coating antibody in association with clone CLB/TF-1 (Cat.-No AM01050PU-N), which recognises a different epitope of CD142.
-
Purification
- Affinity Chromatography on Protein A from tissue culture supernantant.
-
Isotype
- IgG1
-
-
-
-
Indications d'application
-
Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.1 mg/mL
-
Buffer
- Tris buffered saline, pH 8.0 containing, 0.09 % Sodium Azide, 1 % BSA
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
-
: "Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 302, Issue 1, pp. L82-92, (2012) (PubMed).
-
-
- Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
-
Autre désignation
- CD142 / Tissue Factor
-
Sujet
- CD142 is a 45kD cell surface glycoprotein which is otherwise known as Tissue Factor (TF). CD142 expression can be induced on monocytes, macrophages and endothelial cells by various stimuli including interleukin 1, tumour necrosis factor and endotoxin. CD142 initiates the blood clotting cascade by binding coagulation factor VIIa, which activates factor IX or factor X by specific limited proteolysis. CD142 also plays an important role in inflammation, angiogenesis, and the pathophysiology of atherosclerosis and cancer.Synonyms: Coagulation factor III, F3, TF, Thromboplastin
-
ID gène
- 2152
-
NCBI Accession
- NP_001984
-
UniProt
- P13726
-
Pathways
- Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
Antigène
-