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eIF4EBP1 anticorps
EIF4EBP1
Reactivité: Humain
WB, IHC, ELISA
Hôte: Souris
Monoclonal
11G12C11
unconjugated
N° du produit ABIN3209983
Détail du produit anti-eIF4EBP1 anticorps
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Antigène
Voir toutes eIF4EBP1 (EIF4EBP1) Anticorps
eIF4EBP1 (EIF4EBP1)
(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
Reactivité
Toutes les réactivités sur eIF4EBP1 Anticorps
Humain
Hôte
Toutes les hôtes sur eIF4EBP1 Anticorps
Souris
Clonalité
Toutes les clonalités sur eIF4EBP1 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers eIF4EBP1 Anticorps
Cet anticorp eIF4EBP1 est non-conjugé
Application
Tous les applications à travers eIF4EBP1 Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Purification
Purified antibody.
Immunogène
4 EBP1 antibody was raised in Mouse using a purified recombinant fragment of 4 BP1 expressed in E. coli as the immunogen.
Clone
11G12C11
Isotype
IgG1
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Information d'application
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Indications d'application
ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
Lot specific
Buffer
Purified antibody supplied in PBS containing 0.03 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Détails sur eIF4EBP1
(cache)
Antigène
eIF4EBP1 (EIF4EBP1)
(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
Autre désignation
4EBP1 (EIF4EBP1 Produits )
Synonymes
anticorps 4E-BP1, anticorps 4EBP1, anticorps BP-1, anticorps PHAS-I, anticorps 4e-bp1, anticorps AA959816, anticorps 153432_at, anticorps 43-BP, anticorps 4E-BP, anticorps 4EBP, anticorps 4e-bp, anticorps 4eBP, anticorps 4ebp, anticorps BcDNA.HL08053, anticorps BcDNA:HL08053, anticorps CG8846, anticorps CT8705, anticorps Dm 4E-BP, anticorps Dmel\\CG8846, anticorps Phas1, anticorps Thor/EIF4EBP, anticorps anon-WO0172774.158, anticorps d4E-BP, anticorps d4E-BP1, anticorps d4EBP, anticorps d4e-bp, anticorps d4eBP, anticorps dthor, anticorps eIF4E-BP, anticorps l(2)06270, anticorps l(2)k07736, anticorps l(2)k13517, anticorps pp20, anticorps thor, anticorps EIF4EBP1, anticorps fc04h09, anticorps wu:fc04h09, anticorps zgc:64137, anticorps eukaryotic translation initiation factor 4E binding protein 1, anticorps CG8846 gene product from transcript CG8846-RA, anticorps EIF4EBP1, anticorps Eif4ebp1, anticorps Thor, anticorps eif4ebp1
Sujet
4EBP1 which is located on chromosome 8p12, with 118-amino acid protein (about 13kDa). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. 4EBP1 functions as a translation repressor. Synonyms: Monoclonal 4EBP1 antibody, Anti-4EBP1 antibody, 4E-BP1 antibody, 4E BP1 antibody, Eukaryotic translation initiation factor 4E-binding protein 1 antibody, BP-1 antibody, MGC4316 antibody.
Pathways
Signalisation MAPK , Signalisation PI3K-Akt , Signalisation RTK , AMPK Signaling , Regulation of Cell Size , BCR Signaling
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