CD19 anticorps
Aperçu rapide pour CD19 anticorps (ABIN3209992)
Antigène
Voir toutes CD19 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Purified antibody.
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Immunogène
- CD19 antibody was raised in Mouse using a purified recombinant fragment of human CD19 expressed in E. coli as the immunogen.
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Isotype
- IgG2a
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Indications d'application
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ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Concentration
- Lot specific
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Buffer
- Purified antibody supplied in PBS containing 0.03 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C for short term storage. Store at -20 °C for long term storage.
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- CD19 (CD19 Molecule (CD19))
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Autre désignation
- CD19
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Sujet
- CD19 is a protein that in humans is encoded by the CD19 gene. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. Synonyms: Monoclonal CD19 antibody, Anti-CD19 antibody, Cluster of Differentiation 19 antibody, B-lymphocyte antigen CD19 antibody.
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Antigène
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