CD19 anticorps (CD19 Molecule)

Details for Product anti-CD19 Antibody No. ABIN3209992
Antigène
Reactivité
Humain
795
353
74
63
20
20
8
7
5
4
4
4
4
4
4
4
4
2
2
Hôte
Souris
640
222
181
12
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp CD19 est non-conjugé
110
102
79
71
28
22
16
16
15
14
14
13
12
9
9
8
8
8
8
8
7
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
756
204
171
144
128
120
59
54
44
40
22
17
9
8
5
4
4
2
2
1
1
1
1
1
Options
Immunogène CD19 antibody was raised in Mouse using a purified recombinant fragment of human CD19 expressed in E. coli as the immunogen.
Clone 2E2B6B10
Isotype IgG2a
Purification Purified antibody.
Antigène
Autre désignation CD19 (CD19 Antibody Extrait)
Sujet CD19 is a protein that in humans is encoded by the CD19 gene. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. Synonyms: Monoclonal CD19 antibody, Anti-CD19 antibody, Cluster of Differentiation 19 antibody, B-lymphocyte antigen CD19 antibody.
Pathways Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Indications d'application ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.
Restrictions For Research Use only
Concentration Lot specific
Buffer Purified antibody supplied in PBS containing 0.03 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
Stock RT/-20 °C
Stockage commentaire Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Images (Fournisseur)
Image no. 1 for anti-CD19 Molecule (CD19) antibody (ABIN3209992) Immunohistochemical analysis of paraffin-embedded human normal lymph node, showing cy...
Image no. 2 for anti-CD19 Molecule (CD19) antibody (ABIN3209992) Western Blot showing CD19 antibody used against CD19 recombinant protein.