IL-6 Receptor anticorps (Extracellular Domain)

N° du produit ABIN327368

L’anticorps Rat Monoclonal anti-IL-6 Receptor a été validé pour WB et ELISA. Il convient pour détecter IL-6 Receptor dans des échantillons de Souris.

Aperçu rapide pour IL-6 Receptor anticorps (Extracellular Domain) (ABIN327368)

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-6 Receptor est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IL-6 Receptor anticorps

Épitope: Extracellular Domain

Specificité: Recognizes mouse IL-6Ralpha. In direct ELISAs and Western Blots, this antibody does not cross-react with rhIL-6R.

Purification: Protein G purified

Immunogène: NS0-derived rmIL-6Ralpha extracellular domain (aa 20-357) P22272

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, WB

Usage: Western Blot: This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect mouse IL-6 R. Using a colorimetric detection system, the detection limit for rmIL-6 R is approximately 25 ng/lane under non-reducing and reducing conditions. Chemiluminescent detection will increase sensitivity by 5 to 50 fold. Direct ELISA: This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect mouse IL-6 R. The detection limit for rmIL-6 R is approximately 5 ng/well.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 200 μL sterile PBS

Concentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.4, 5 % trehalose.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur IL-6 Receptor

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Autre désignation: IL6R / IL6 Receptor

Sujet: Name/Gene ID: IL6R
Family: Interleukin

Synonyms: IL6R, CD126, gp80, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, IL-6 receptor subunit alpha, IL-6R 1, IL-6R-1, Interleukin 6 receptor, Membrane glycoprotein 80, CD126 antigen, IL6RA, IL6RQ

ID gène: 3570

UniProt: P08887

Pathways: Signalistation JAK/STAT, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints