Mesothelin anticorps

N° du produit ABIN328471

Cet anticorps Rat Monoclonal détecte spécifiquement Mesothelin dans ELISA et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Mesothelin anticorps (ABIN328471)

Antigène: Mesothelin (MSLN)

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Mesothelin est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Détail du produit anti-Mesothelin anticorps

Specificité: Recognizes human mesothelin. This antibody binds to mesothelin cleaved form which is the ~40 kDa cell membrane-associated glycosylphosphatidylinositol-linked glycoprotein. It is not expected to react with the soluble portion of the mesothelin precursor protein that is designated as the megakaryocyte potentiating factor.

Purification: Immunoaffinity purified

Immunogène: NS0-derived recombinant human mesothelin.

Type of Immunogen: Recombinant protein

Isotype: IgG2a

Information d'application

Indications d'application: Approved: ELISA (0.5 - 1 μg/mL), Flo (2.5 μg/10 x10⁶)

Usage: Flow Cytometry: This antibody was validated for flow cytometry using Hela human cervical carcinoma cells. Use at 2.5 μg per 10e6 cells. Direct ELISA: 0.5-1.0 μg/mL with the appropriate secondary reagents to detect human Mesothelin. The detection limit for rhMesothelin is approximately 5 ng/well.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 200 μL sterile PBS

Concentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.4, 5 % trehalose

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur Mesothelin

Antigène: Mesothelin (MSLN)

Autre désignation: MSLN / Mesothelin

Sujet: Name/Gene ID: MSLN

Synonyms: MSLN, CAK1 antigen, MPF, SMRP, Mesothelin, CAK1

ID gène: 10232

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process