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Nestin anticorps

NES Reactivité: Humain WB, IHC, ICC, IHC (p), IHC (fro) Hôte: Souris Monoclonal 10C2 unconjugated
N° du produit ABIN335378
  • Antigène Voir toutes Nestin (NES) Anticorps
    Nestin (NES)
    Reactivité
    • 132
    • 69
    • 51
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 103
    • 39
    • 4
    • 2
    • 1
    Souris
    Clonalité
    • 108
    • 41
    Monoclonal
    Conjugué
    • 66
    • 10
    • 10
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Cet anticorp Nestin est non-conjugé
    Application
    • 82
    • 51
    • 49
    • 48
    • 41
    • 40
    • 39
    • 29
    • 25
    • 15
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    10C2 reacts exclusively with the human nestin protein. No cross-reactivity to rodent nestin.
    Purification
    Purified
    Immunogène
    Nestin (clone 10C2) is a monoclonal antibody derived by traditional hybridoma technology. A 150-amino-acid fragment from the cloned human nestin was conjugated to glutathione S-transferase and used as an immunogen.
    Clone
    10C2
    Isotype
    IgG1
    Top Product
    Discover our top product NES Anticorps primaire
  • Restrictions
    For Research Use only
  • Stock
    -20 °C
  • Sellheyer, Krahl: "Does the peritumoral stroma of basal cell carcinoma recapitulate the follicular connective tissue sheath?" dans: Journal of cutaneous pathology, Vol. 38, Issue 7, pp. 551-9, (2011) (PubMed).

    Elamin, Shinwari, Hendrayani, Al-Hindi, Al-Shail, Khafaga, Al-Kofide, Aboussekhra: "Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells." dans: Molecular carcinogenesis, Vol. 49, Issue 3, pp. 302-14, (2010) (PubMed).

    Popescu, Manole, Gherghiceanu, Ardelean, Nicolescu, Hinescu, Kostin: "Telocytes in human epicardium." dans: Journal of cellular and molecular medicine, Vol. 14, Issue 8, pp. 2085-93, (2010) (PubMed).

    Sellheyer, Krahl et al.: "Spatiotemporal expression pattern of neuroepithelial stem cell marker nestin suggests a role in dermal homeostasis, neovasculogenesis, and tumor stroma development: a study on embryonic and adult ..." dans: Journal of the American Academy of Dermatology, Vol. 63, Issue 1, pp. 93-113, (2010) (PubMed).

    Murphy, Viero, Ho, Thorner: "Diagnostic utility of nestin expression in pediatric tumors in the region of the kidney." dans: Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry, Vol. 17, Issue 6, pp. 517-23, (2009) (PubMed).

    Mokry, Pudil, Ehrmann, Cizkova, Osterreicher, Filip, Kolar: "Re-expression of nestin in the myocardium of postinfarcted patients." dans: Virchows Archiv : an international journal of pathology, Vol. 453, Issue 1, pp. 33-41, (2008) (PubMed).

    Corsino, Davis, Nørgaard, Parker, Law, Dunn, Law: "Mammary tumors initiated by constitutive Cdk2 activation contain an invasive basal-like component." dans: Neoplasia (New York, N.Y.), Vol. 10, Issue 11, pp. 1240-52, (2008) (PubMed).

    Hou, Tan, Xu, Wang, Lu, Ji, Wang, Zhu: "Schwannoma of the gastrointestinal tract: a clinicopathological, immunohistochemical and ultrastructural study of 33 cases." dans: Histopathology, Vol. 48, Issue 5, pp. 536-45, (2006) (PubMed).

    Messam, Hou, Major: "Coexpression of nestin in neural and glial cells in the developing human CNS defined by a human-specific anti-nestin antibody." dans: Experimental neurology, Vol. 161, Issue 2, pp. 585-96, (2000) (PubMed).

  • Antigène
    Nestin (NES)
    Autre désignation
    Nestin (NES Produits)
    Synonymes
    anticorps paranemin, anticorps NES, anticorps AA166324, anticorps C78523, anticorps ESTM46, anticorps nestin, anticorps nestin S homeolog, anticorps NES, anticorps nes.S, anticorps Nes, anticorps nes
    Sujet
    Nestin is a Class IV intermediate filament protein abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. This cytoskeletal protein has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, it is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. These highly specific antibodies to human nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells.
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