Caspase 6 anticorps (Cleavage Site)
Aperçu rapide pour Caspase 6 anticorps (Cleavage Site) (ABIN337396)
Antigène
Voir toutes Caspase 6 (CASP6) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Cleavage Site
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Marque
- IHC-plus™
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Specificité
- Caspase-6 Antibody recognizes endogenous levels of both full length caspase-6 (35kD) and the small subunit of caspase-6 resulting from cleavage at Asp194 (15kD). This antibody does not recognize other caspases. Recognizes human, mouse, rabbit.
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Purification
- Protein A purified
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Immunogène
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Synthetic peptide KLH coupled corresponding to residues surrounding the cleavage site of caspase-6.
Type of Immunogen: Synthetic peptide -
Isotype
- IgG
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Indications d'application
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Approved: ELISA, IHC, IHC-P (5 μg/mL), WB (1:1000)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. -
Commentaires
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Target Species of Antibody: Mouse
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
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Autre désignation
- CASP6 / Caspase 6
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Sujet
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Name/Gene ID: CASP6
Subfamily: Cysteine C14
Family: Protease
Synonyms: CASP6, Apoptotic protease Mch-2, Caspase 6, CASP-6, Caspase-6, Mch-2, MCH2 -
ID gène
- 839
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UniProt
- P55212
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Pathways
- Apoptose, Caspase Cascade in Apoptosis
Antigène
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