MTA2 anticorps (AA 652-668)

N° du produit ABIN342361

Cet anticorps Lapin Polyclonal détecte spécifiquement MTA2 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MTA2 anticorps (AA 652-668) (ABIN342361)

Antigène: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTA2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MTA2 anticorps

Épitope: AA 652-668

Specificité: Recognizes human, mouse, and rat PID/MTA2, a subunit of the nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex, and its expression reduces the levels of acetylated p53. Deacetylation of p53 by PID/MTA2 represses p53- dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is expressed in a variety of tissues. Does not cross-react with MTA1.

Purification: Immunoaffinity purified

Immunogène: Peptide corresponding to aa 652-668 of human PID/MTA2. This sequence differs from that of mouse by one amino acid.

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: WB (0.5 - 1 μg/mL)

Usage: Western Blot: A band of 75 kD is detected.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur MTA2

Antigène: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Autre désignation: MTA2

Sujet: Name/Gene ID: MTA2

Synonyms: MTA2, Metastasis-associated 1-like 1, MTA1L1, PID, MTA1-L1, MTA1-L1 protein

ID gène: 9219

UniProt: O94776

Pathways: Chromatin Binding