CD14 anticorps (AA 33-44)

N° du produit ABIN343171

Cet anticorps Souris Monoclonal détecte spécifiquement CD14 dans FACS et Agon. Il présente une réactivité envers Humain.

Aperçu rapide pour CD14 anticorps (AA 33-44) (ABIN343171)

Antigène: CD14

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD14 est non-conjugé

Application: Flow Cytometry (FACS), Agonist (Agon)

Clone: BiG4

Détail du produit anti-CD14 anticorps

Épitope: AA 33-44

Specificité: Soluble and membrane bound human CD14. The antibody don't block LPS binding to membrane bound CD14.

Purification: Protein A affinity column

Immunogène: human Monocytes

Isotype: IgG2a

Information d'application

Indications d'application: no significant inhibition of LPS binding to CD14

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with bidistilled water

Concentration: 1 mg/mL

Buffer: PBS, pH 7.8

Agent conservateur: Without preservative

Stock: -20 °C,-80 °C

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: Background: biG 4 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.

Poids moléculaire: ~50kDa

ID gène: 929

NCBI Accession: NP_000582

UniProt: P08571

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades