CD14 anticorps

N° du produit ABIN343181

L’anticorps Lapin Polyclonal anti-CD14 a été validé pour FACS, IP et Func. Il convient pour détecter CD14 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour CD14 anticorps (ABIN343181)

Antigène: CD14

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD14 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Détail du produit anti-CD14 anticorps

Purification: Protein G purified

Immunogène: Affinity purified recombinant human CD14

Information d'application

Indications d'application: Suitable for Immunostaining of CD14 positive cells, Immunoprecipitation, Western blot. no significant but small inhibition of LPS binding to human CD14, Binding titre at human CD14+CHO cells (FACS) more than 1:5.000. Recommended working dilution: 1: 100 till 1.000 Binding at mouse CD14 transfected CHO+ cells more than 1:1000 (recommanded working dilution 1:10 til 1:100)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.1 ml without NaN3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-CD14 (ABIN343181)

Baveye, Elass, Fernig, Blanquart, Mazurier, Legrand: "Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex." dans: Infection and immunity, Vol. 68, Issue 12, pp. 6519-25, (2000) (PubMed).

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: The antiserum represents a marker for human CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for endotoxin.

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades