Caldesmon anticorps
Aperçu rapide pour Caldesmon anticorps (ABIN347045)
Antigène
Voir toutes Caldesmon (CALD1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Reacts with human L-Caldesmon
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Purification
- Antiserum
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Immunogène
- A 15 residue synthetic peptide derived from human L-Caldesmon
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Isotype
- IgG
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Indications d'application
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC(1:50 - 1:500) WB(1:200- 1:5000) -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Must be reconstituted in distilled water.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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Date de péremption
- 24 months
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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Autre désignation
- L-Caldesmon
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Sujet
- Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration
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ID gène
- 800
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UniProt
- Q05682
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Pathways
- Myometrial Relaxation and Contraction
Antigène
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