KIT anticorps (N-Term)

N° du produit ABIN347451

Cet anticorps anti-KIT Polyclonal Lapin (ABIN347451) détecte spécifiquement KIT dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour KIT anticorps (N-Term) (ABIN347451)

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIT est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-KIT anticorps

Épitope: N-Term

Specificité: Reacts with human 110 kDa c-kit

Réactivité croisée: Souris

Réactivité croisée (Details): May cross react with pig, cat, goat, dog, bovin, mouse proteins.

Purification: Antiserum

Immunogène: Synthetic peptide derived from N-term domain of the human c-Kit protein.

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/500 - WB : 1/500 to 1/2 000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur KIT

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Autre désignation: CD117/ C-Kit

Sujet: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways

ID gène: 3815

UniProt: P10721

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity