Beclin 1 anticorps

N° du produit ABIN349986

Cet anticorps anti-Beclin 1 est un anticorps Mouton Polyclonal détectant Beclin 1 dans WB et IHC. Adapté pour Humain.

Aperçu rapide pour Beclin 1 anticorps (ABIN349986)

Antigène: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp Beclin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Beclin 1 anticorps

Fonction: Sheep antibody to Beclin 1

Specificité: Specific for Beclin-1.

Réactivité croisée: Humain, Marmoset, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from human Beclin-1 conjugated to blue carrier protein has been used as the antigen. The antigen is homologous in rat and mouse.

Isotype: IgG

Information d'application

Indications d'application: IHC WB. Use at a concentration of 10-50,micro,g,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur Beclin 1

Antigène: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Autre désignation: Beclin 1

Sujet: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation metamorphosis non-apoptotic cell death and aging. Reduced levels of autophagy have been described in some malignant tumors and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. It may play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role in autophagy. SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus membrane, Peripheral membrane protein. Note: Expressed in dendrites and cell bodies of cerebellar Purkinje cells TISSUE SPECIFICITY: Ubiquitous

UniProt: Q14457

Pathways: Autophagy