ACCN1 anticorps (AA 470-503)

N° du produit ABIN350042

L’anticorps Lapin Polyclonal anti-ACCN1 a été validé pour WB et IHC. Il convient pour détecter ACCN1 dans des échantillons de Humain.

Aperçu rapide pour ACCN1 anticorps (AA 470-503) (ABIN350042)

Antigène: ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACCN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ACCN1 anticorps

Épitope: AA 470-503

Fonction: Rabbit antibody to ASIC2 (470-503)

Specificité: Specific for ASIC2.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from AA 470-503 of human ASIC2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Isotype: IgG

Information d'application

Indications d'application: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur ACCN1

Antigène: ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Autre désignation: ASIC2

Sujet: FUNCTION: Cation channel with high affinity for sodium which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate. SUBUNIT: Homotetramer or heterotetramer with other ASIC proteins. Interacts with STOM. Interacts with PRKCABP and ACCN3. SUBCELLULAR LOCATION: Cell membrane, Multi-pass membrane protein. Note: Localized at the plasma membrane of neurons in the soma and punctated peripheral processes.

UniProt: Q16515

Pathways: Sensory Perception of Sound