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NGFR anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement NGFR dans WB, IHC et ELISA. Il présente une réactivité envers Rat.
N° du produit ABIN350707

Aperçu rapide pour NGFR anticorps (ABIN350707)

Antigène

Voir toutes NGFR Anticorps
NGFR (Nerve Growth Factor Receptor (NGFR))

Reactivité

  • 203
  • 62
  • 54
  • 38
  • 30
  • 28
  • 27
  • 22
  • 12
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Rat

Hôte

  • 107
  • 102
  • 4
  • 1
Souris

Clonalité

  • 139
  • 75
Monoclonal

Conjugué

  • 94
  • 18
  • 12
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp NGFR est non-conjugé

Application

  • 114
  • 90
  • 87
  • 59
  • 42
  • 41
  • 28
  • 27
  • 21
  • 17
  • 15
  • 15
  • 12
  • 7
  • 6
  • 6
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Fonction

    Mouse monoclonal antibody to rat p75NTR (MC192)

    Specificité

    Specific for rat p75NTR.

     Réactivité croisée

    Rat

    Purification

    Affinity purified

    Immunogène

    Nerve growth factor receptor (TNFR superfamily member 16)
  • Indications d'application

    WB IHC ELISA. A working concentration of 5-15 μg,ml is recommended. This antibody is suitable for use in paraformaldehyde fixed alcohol fixed,paraffin-embedded sections. The optimal working solution should be determined by the end user.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

    Conseil sur la manipulation

    Avoid freeze and thaw cycles.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    Date de péremption

    12 months
  • Antigène

    NGFR (Nerve Growth Factor Receptor (NGFR))

    Autre désignation

    p75NTR

    Sujet

    FUNCTION: Low affinity receptor which can bind to NGF BDNF NT-3 and NT-4. Can mediate cell survival as well as cell death of neural cells. SUBUNIT: Homodimer, disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with NGFRAP1/BEX3. Interacts with TRAF2 TRAF4 TRAF6 PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.

    Pathways

    Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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