EHMT1 anticorps (AA 956-986)
Aperçu rapide pour EHMT1 anticorps (AA 956-986) (ABIN356610)
Antigène
Voir toutes EHMT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 956-986
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Specificité
- This antibody is specific to Human EUHMTASE1 (Center).
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Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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Immunogène
- KLH conjugated synthetic peptide between 956~986 amino acids from the Center region of Human EUHMTASE1
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))
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Autre désignation
- EHMT1
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Sujet
- EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.Synonyms: EUHMTASE1, Eu-HMTase1, Euchromatic histone-lysine N-methyltransferase 1, G9a-like protein 1, GLP, GLP1, H3-K9-HMTase 5, Histone H3-K9 methyltransferase 5, Histone-lysine N-methyltransferase EHMT1, KIAA1876, KMT1D, Lysine N-methyltransferase 1D
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ID gène
- 79813, 9606
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UniProt
- Q9H9B1
Antigène
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