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NEDD8 anticorps (N-Term)

NEDD8 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN356744
  • Antigène Voir toutes NEDD8 Anticorps
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    Épitope
    • 15
    • 12
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 66
    • 29
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 63
    • 4
    • 4
    Lapin
    Clonalité
    • 59
    • 12
    Polyclonal
    Conjugué
    • 30
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NEDD8 est non-conjugé
    Application
    • 38
    • 27
    • 27
    • 13
    • 13
    • 12
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody is specific to NEDD8 (N-term).
    Purification
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human NEDD8.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NEDD8 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    Autre désignation
    NEDD8 (NEDD8 Produits)
    Synonymes
    anticorps NEDD-8, anticorps Rub1, anticorps CG10679, anticorps Dmel\\CG10679, anticorps NEDD8, anticorps dNEDD8, anticorps nedd8, anticorps ubiquitin, anticorps si:zc14a17.5, anticorps GB17785, anticorps DDBDRAFT_0218116, anticorps DDBDRAFT_0238041, anticorps DDB_0218116, anticorps DDB_0238041, anticorps nedd8.S, anticorps neural precursor cell expressed, developmentally down-regulated 8, anticorps neural precursor cell expressed, developmentally down-regulated gene 8, anticorps CG10679 gene product from transcript CG10679-RB, anticorps Nedd8, anticorps ubiquitin-like protein Nedd8, anticorps neural precursor cell expressed, developmentally down-regulated 8 L homeolog, anticorps NEDD8, anticorps Nedd8, anticorps nedd8, anticorps nedd8.L
    Sujet
    NEDD8 is a ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.Synonyms: Neural precursor cell expressed developmentally down-regulated protein 8
    ID gène
    4738, 9606
    UniProt
    Q15843
    Pathways
    Ubiquitin Proteasome Pathway
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