Stanniocalcin 2 anticorps (N-Term)

N° du produit ABIN356935

Cet anticorps Lapin Polyclonal détecte spécifiquement Stanniocalcin 2 dans WB, IHC (p) et EIA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Stanniocalcin 2 anticorps (N-Term) (ABIN356935)

Antigène: Stanniocalcin 2 (STC2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Stanniocalcin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Stanniocalcin 2 anticorps

Épitope: N-Term

Specificité: This antibody detects STC2 at N-term.

Purification: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: KLH conjugated synthetic peptide selected from the N-terminal region of human STC2

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA1: 1,000. Western blotting 1: 100 - 1: 500. Immunohistochemistry: 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur Stanniocalcin 2

Antigène: Stanniocalcin 2 (STC2)

Autre désignation: Stanniocalcin 2 / STC2

Sujet: STC2 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression is induced by estrogen and altered in some breast cancers.Synonyms: STC-2, STC-related protein, STCRP, Stanniocalcin-2, Stanniocalcin-related protein

Poids moléculaire: 33249 Da

ID gène: 8614, 9606

UniProt: O76061

Pathways: Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome