RENT1/UPF1 anticorps (N-Term)

N° du produit ABIN357204

Cet anticorps anti-RENT1/UPF1 est un anticorps Lapin Polyclonal détectant RENT1/UPF1 dans EIA. Adapté pour Humain et Souris.

Aperçu rapide pour RENT1/UPF1 anticorps (N-Term) (ABIN357204)

Antigène: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RENT1/UPF1 est non-conjugé

Application: Enzyme Immunoassay (EIA)

Détail du produit anti-RENT1/UPF1 anticorps

Épitope: N-Term

Specificité: This antibody detects RENT1 at N-term.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human RENT1.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur RENT1/UPF1

Antigène: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Autre désignation: UPF1 / RENT1

Sujet: RENT1 is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.Synonyms: ATP-dependent helicase RENT1, KIAA0221, NORF1, Nonsense mRNA reducing factor 1, Regulator of nonsense transcripts 1, Up-frameshift suppressor 1 homolog

Poids moléculaire: 124345 Da

ID gène: 5976, 9606

UniProt: Q92900

Pathways: SARS-CoV-2 Protein Interactome