SYVN1 anticorps (C-Term)
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- Antigène Voir toutes SYVN1 Anticorps
- SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SYVN1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody is specific for SYVN1/HRD1 (C-term). Predicted to cross react with Mouse (100 % Antigen Homology).
- Réactivité croisée (Details)
- Species reactivity (tested):Human and Mouse.
- Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human HRD1.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SYVN1 Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
- Autre désignation
- SYVN1 (SYVN1 Produits)
- Synonymes
- anticorps DER3, anticorps HRD1, anticorps hrd1, anticorps 1200010C09Rik, anticorps AW211966, anticorps C85322, anticorps D530017H19Rik, anticorps Hrd1, anticorps RGD1310488, anticorps syvn1, anticorps syvn1-a, anticorps syvn1-b, anticorps wu:fk91f10, anticorps zgc:55735, anticorps zgc:77108, anticorps synoviolin 1, anticorps synovial apoptosis inhibitor 1, synoviolin, anticorps synoviolin 1 S homeolog, anticorps SYVN1, anticorps syvn1, anticorps Syvn1, anticorps syvn1.S
- Sujet
- HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. Amano T, et al. reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its antiapoptotic effects. HRD1 contains one ring-type zinc finger.Synonyms: E3 ubiquitin-protein ligase synoviolin, HRD1, KIAA1810, Synovial apoptosis inhibitor 1, Synoviolin
- Poids moléculaire
- 67612 Da
- ID gène
- 84447, 5874
- UniProt
- Q86TM6
- Pathways
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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