CDK7 anticorps (pThr170)
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- Antigène Voir toutes CDK7 Anticorps
- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
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Épitope
- pThr170
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDK7 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects CDK7 pThr170. Predicted to cross react with Mouse (100 % Antigen Homology).
- Purification
- Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T170 of human CDK7.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CDK7 Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
- Autre désignation
- CDK7 (CDK7 Produits)
- Synonymes
- anticorps CAK1, anticorps CDKN7, anticorps HCAK, anticorps MO15, anticorps STK1, anticorps p39MO15, anticorps AI323415, anticorps AI528512, anticorps C230069N13, anticorps Cdkn7, anticorps Crk4, anticorps CD 7, anticorps CDK7, anticorps CG3319, anticorps DmCDK7, anticorps DmCdk7, anticorps DmMO15, anticorps DmMo15, anticorps Dmcdk7, anticorps Dmel\\CG3319, anticorps Mo15, anticorps cdk-7, anticorps cdk7, anticorps dCdk7, anticorps p40[MO15], anticorps p40MO15, anticorps stk1, anticorps zgc:85821, anticorps cak1, anticorps cdkn7, anticorps p39mo15, anticorps cyclin dependent kinase 7, anticorps cyclin-dependent kinase 7, anticorps Cyclin-dependent kinase 7, anticorps cyclin-dependent kinase 7 L homeolog, anticorps CDK7, anticorps Cdk7, anticorps cdk7.L, anticorps cdk7
- Sujet
- The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.Synonyms: 39 kDa protein kinase, CAK1, CDK-activating kinase, Cell division protein kinase 7, P39 Mo15, STK1, TFIIH basal transcription factor complex kinase subunit
- Poids moléculaire
- 39038 Da
- ID gène
- 1022, 9606
- UniProt
- P50613
- Pathways
- Cycle Cellulaire, Réparation de l'ADN, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
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