MAPKAP Kinase 5 anticorps (pSer93)
Aperçu rapide pour MAPKAP Kinase 5 anticorps (pSer93) (ABIN358154)
Antigène
Voir toutes MAPKAP Kinase 5 (MAPKAPK5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer93
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Specificité
- This antibody detects MAPKAP Kinase-5 (MAPKAPK5) pSer93.
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Purification
- Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S93 of Human MAPKAPK. Genename: MAPKAPK5
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
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Autre désignation
- MAPKAP Kinase-5
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Sujet
- The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites.Synonyms: MAP kinase-activated protein kinase 5, MAPK-activated protein kinase 5, MAPKAP kinase 5, MAPKAPK5, PRAK
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Poids moléculaire
- 54220 Da
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ID gène
- 8550, 9606
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UniProt
- Q8IW41
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Pathways
- Signalisation MAPK
Antigène
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