CDC25A anticorps (pSer79)

N° du produit ABIN358452

Détail du produit anti-CDC25A anticorps

Antigène: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Épitope: pSer79

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC25A est non-conjugé

Application: Enzyme Immunoassay (EIA)

Specificité: This antibody detects Cdc25A pSer79. Predicted to cross react with Mouse (100 % Antigen Homology).

Purification: Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S79 of human Cdc25A.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur CDC25A

Antigène: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Autre désignation: CDC25A (CDC25A Produits)

Synonymes: anticorps cdc25a2, anticorps cdc25A, anticorps sb:cb317, anticorps CDC25A2, anticorps D9Ertd393e, anticorps cell division cycle 25A, anticorps cell division cycle 25B, anticorps cell division cycle 25A S homeolog, anticorps CDC25A, anticorps cdc25a, anticorps cdc25b, anticorps Cdc25a, anticorps cdc25a.S

Sujet: CDC25A is a member of the CDC25 family of phosphatases.CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division.CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.Synonyms: CDC-25A, Cell Division Cycle 25A, Dual specificity phosphatase Cdc25A, M-phase inducer phosphatase 1

Poids moléculaire: 59087 Da

ID gène: 993, 9606

UniProt: P30304

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase