NAE1 anticorps (C-Term)
Aperçu rapide pour NAE1 anticorps (C-Term) (ABIN359509)
Antigène
Voir toutes NAE1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Specificité
- This antibody detects NAE1 (APPBP1) at C-term.
-
Purification
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
-
Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human APPBP1.
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
-
ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry on paraffin sections 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.25 mg/mL
-
Buffer
- PBS with 0.09 % (W/V) sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
-
-
- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
-
Autre désignation
- APPBP1
-
Sujet
- APPBP1 binds to the beta-amyloid precursor protein, a cell surface protein with signal-transducing properties thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPB1 is required for cell cycle progression through the S/M checkpoint.Synonyms: Amyloid beta precursor protein-binding protein 1, Amyloid protein-binding protein 1, HPP1, NAE1
-
Poids moléculaire
- 60252 Da
-
ID gène
- 8883, 9606
-
UniProt
- Q13564
Antigène
-