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HCK anticorps (N-Term)

L’anticorps Lapin Polyclonal anti-HCK a été validé pour WB et EIA. Il convient pour détecter HCK dans des échantillons de Humain.
N° du produit ABIN359984

Aperçu rapide pour HCK anticorps (N-Term) (ABIN359984)

Antigène

Voir toutes HCK Anticorps
HCK (Hemopoietic Cell Kinase (HCK))

Reactivité

  • 80
  • 30
  • 18
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 73
  • 8
  • 1
Lapin

Clonalité

  • 75
  • 7
Polyclonal

Conjugué

  • 45
  • 5
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp HCK est non-conjugé

Application

  • 66
  • 40
  • 21
  • 14
  • 13
  • 11
  • 11
  • 6
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Épitope

    • 15
    • 10
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificité

    This antibody reacts to HCK.

    Purification

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    Immunogène

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human HCK.

    Isotype

    Ig Fraction
  • Indications d'application

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène

    HCK (Hemopoietic Cell Kinase (HCK))

    Autre désignation

    HCK

    Sujet

    HCK is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.Synonyms: B-cell/myeloid kinase, BMK, Hemopoietic cell kinase, Tyrosine-protein kinase HCK, p56-HCK, p59-HCK, p60-HCK

    ID gène

    3055, 9606

    UniProt

    P08631

    Pathways

    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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