Aurora A anticorps (N-Term)
Aperçu rapide pour Aurora A anticorps (N-Term) (ABIN360272)
Antigène
Voir toutes Aurora A (AURKA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody recognizes Aurora kinase A.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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Immunogène
- KLH conjugated synthetic peptide selected from the N-terminal region of Human AIK. Genename: AURKA
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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Autre désignation
- Aurora Kinase A
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Sujet
- Aurora A (AIK) plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Synonyms: AIK1, ARK1, AURA, AURKA, AURORA2, Aurora/IPL1-related kinase 1, BTAK, Breast tumor-amplified kinase, STK15, STK6, Serine/threonine kinase 15, Serine/threonine-protein kinase 6
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ID gène
- 6790, 5874
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UniProt
- O14965
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Pathways
- Cycle Cellulaire, Asymmetric Protein Localization
Antigène
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