MAP3K14 anticorps (Middle Region)
Aperçu rapide pour MAP3K14 anticorps (Middle Region) (ABIN360384)
Antigène
Voir toutes MAP3K14 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Specificité
- This antibody reacts to NFkB Inducing Kinase (NIK).
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Purification
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human NIK.
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
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Autre désignation
- MAP3K14
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Sujet
- NIK (mitogen-activated protein kinase kinase kinase 14), a member of the Ser/Thr protein kinase family, binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.Synonyms: Mitogen-activated protein kinase kinase kinase 14, NF-kappa beta-inducing kinase, Serine/threonine-protein kinase NIK
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ID gène
- 9020
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NCBI Accession
- NP_003945
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UniProt
- Q99558
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Pathways
- Signalisation NF-kappaB, TCR Signaling
Antigène
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