FGF10 anticorps (C-Term)

N° du produit ABIN360398

Il existe 1 publication pour ce produit. L’anticorps anti-FGF10 Polyclonal Lapin est utilisé pour la détection de FGF10 dans des échantillons de Humain. Il a été validé pour EIA et IHC (p).

Aperçu rapide pour FGF10 anticorps (C-Term) (ABIN360398)

Antigène: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF10 est non-conjugé

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-FGF10 anticorps

Épitope: C-Term

Specificité: This antibody reacts to FGF10.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human FGF10.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Références pour anticorps anti-FGF10 (ABIN360398)

El Agha, Moiseenko, Kheirollahi, De Langhe, Crnkovic, Kwapiszewska, Kosanovic, Schwind, Schermuly, Henneke, MacKenzie, Quantius, Herold, Ntokou, Ahlbrecht, Morty, Günther, Seeger, Bellusci: "Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis." dans: Cell stem cell, Vol. 20, Issue 2, pp. 261-273.e3, (2016) (PubMed).

Détails sur FGF10

Antigène: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Autre désignation: FGF10

Sujet: FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.Synonyms: FGF-10, Fibroblast growth factor 10, KGF2, Keratinocyte growth factor 2

ID gène: 2255, 9606

UniProt: O15520

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus