IGFBP6 anticorps

N° du produit ABIN360903

Cet anticorps anti-IGFBP6 Monoclonal Rat (Clone 21D24) (ABIN360903) détecte spécifiquement IGFBP6 dans WB. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour IGFBP6 anticorps (ABIN360903)

Antigène: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IGFBP6 est non-conjugé

Application: Western Blotting (WB)

Clone: 21D24

Détail du produit anti-IGFBP6 anticorps

Purification: Protein A/G affinity chromatography

Immunogène: Recombinant protein of IGF-BP6

Isotype: IgG2

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IGFBP6

Antigène: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Autre désignation: IGFBP6

Sujet: IGFBP6 (IGF binding protein 6) is a member of the IGFBP family that regulates the actions of IGFs. It acts extracellularly in an autocrine/paracrine manner. IGFBP6 binds preferentially to IGF-II. IGFBP6 has been shown to inhibit the growth of tumour cells and to promote apotosis. IGFBP6 has been shown to be imported into the nuclei of rhabdomyosarcoma and HEK-293 cells. This is mediated by a NLS sequence that bears limited homology to those found in IGFBP-3 and -5. Deletion of the NLS segment abolishes the pro-apoptotic effect of IGFBP6.Synonyms: IBP-6, IBP6, IGF-binding protein 6, IGFBP-6, Insulin-like growth factor-binding protein 6

ID gène: 10090

UniProt: P47880

Pathways: Signalisation WNT, Myometrial Relaxation and Contraction