IL3RA anticorps (Extracellular Domain)

N° du produit ABIN360906

Cet anticorps anti-IL3RA est un anticorps Rat Monoclonal détectant IL3RA dans WB. Adapté pour Souris.

Aperçu rapide pour IL3RA anticorps (Extracellular Domain) (ABIN360906)

Antigène: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL3RA est non-conjugé

Application: Western Blotting (WB)

Clone: 9G52

Détail du produit anti-IL3RA anticorps

Épitope: Extracellular Domain

Specificité: This antibody detects IL-3Ralpha. Do not cross react to IL-3Rbeta.

Purification: Protein A/G affinity chromatography

Immunogène: Recombinant protein of IL-3Ralpha extracellular domain.

Isotype: IgG2

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IL3RA

Antigène: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Autre désignation: CD123 / IL3RA

Sujet: IL3RA (CD123) is a member of the immunoglobulin superfamily that is expressed on hematopoietic progenitors, basophils, mast cells, and megakaryocytes. This transmembrane glycoprotein can bind IL3 with low affinity but cannot transduce signals without association with additional protein partners. CD123 can complex with either common beta chain (CDw131) or the IL3RB chain to form high affinity heterodimeric IL3 receptors. CDw131 can complex with the Alpha subunits of the mouse IL3R, IL5R and GMCSFR to form high affinity receptors, while the IL3RB subunit is specific for IL3 but binds with low affinity. IL3 binding to the receptor complex can induce proliferation and differentiation of hematopoietic cells. It is present in Hematopoietic progenitors, basophils, mast cells and megakaryocytes.Synonyms: IL-3R-alpha, IL3 receptor alpha, Interleukin-3 receptor subunit alpha

ID gène: 16188

NCBI Accession: NP_032395

UniProt: P26952

Pathways: Signalistation JAK/STAT