Connexin 43/GJA1 anticorps (C-Term)
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- Antigène Voir toutes Connexin 43/GJA1 (GJA1) Anticorps
- Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
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Épitope
- C-Term
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Connexin 43/GJA1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- Specific for the ~43k connexin43 protein.
- Réactivité croisée
- Rat (Rattus)
- Homologie
- chicken, canine, finch, human, mouse non-human primate, sheep, Xenopus, zebra fish
- Purification
- Antigen Affinity Purified from Pooled Serum
- Immunogène
- Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH
- Top Product
- Discover our top product GJA1 Anticorps primaire
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- Indications d'application
- Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- Stock
- -20 °C
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- Antigène
- Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
- Autre désignation
- GJA1 (GJA1 Produits)
- Synonymes
- anticorps AVSD3, anticorps CX43, anticorps DFNB38, anticorps GJAL, anticorps HLHS1, anticorps HSS, anticorps ODDD, anticorps Cx43, anticorps AU042049, anticorps AW546267, anticorps Cnx43, anticorps Cx43alpha1, anticorps Gja-1, anticorps Npm1, anticorps connexin43, anticorps cx43a1, anticorps gja1, anticorps zfCx43.3, anticorps connexin 43, anticorps gja1-A, anticorps cx43, anticorps gjal, anticorps oddd, anticorps dfnb38, anticorps gap junction protein alpha 1, anticorps gap junction protein, alpha 1, anticorps connexin 43, anticorps gap junction protein alpha 1 L homeolog, anticorps CONNEXIN 43 protein, anticorps GJA1, anticorps Gja1, anticorps cx43, anticorps gja1.L, anticorps gja1, anticorps CONNEXIN 43
- Sujet
- Gap junctional intercellular communication is thought to play a key role in development and may also be involved in epilepsy (Aronica et al., 2001). Connexin43 forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at er368 by protein kinase C (Yogo et al., 2002, Bao et al., 2004a). Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability (Bao et al., 2004b). Anti-Connexin43 Western blot of rat cerebellar lysate showing specific immunolabeling of the ~43k connexin43 protein.
- Poids moléculaire
- '43 kDa
- ID gène
- 24392
- UniProt
- P08050
- Pathways
- Signalisation MAPK, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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