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VEGFR2/CD309 anticorps (pTyr1175)
VEGFR2
Reactivité: Humain, Souris, Rat
IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-VEGFR2/CD309 anticorps
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Antigène
Voir toutes VEGFR2/CD309 (VEGFR2) Anticorps
VEGFR2/CD309 (VEGFR2)
(VEGF Receptor 2 (VEGFR2))
Épitope
Tous les épitopes à travers VEGFR2/CD309 Anticorps.
pTyr1175
Reactivité
Toutes les réactivités sur VEGFR2/CD309 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur VEGFR2/CD309 Anticorps
Lapin
Clonalité
Toutes les clonalités sur VEGFR2/CD309 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers VEGFR2/CD309 Anticorps
Cet anticorp VEGFR2/CD309 est non-conjugé
Application
Tous les applications à travers VEGFR2/CD309 Anticorps.
Immunohistochemistry (IHC), Immunofluorescence (IF)
Specificité
The Antibody detects endogenous level of VEGFR2 only when phosphorylated at tyrosine 1175.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Immunogène
Peptide sequence around phosphorylation site of pTyr1175 (K-D-Y (p) -I-V) derived from Human VEGFR2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
Isotype
IgG
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Discover our top product VEGFR2 Anticorps primaire
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Information d'application
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Indications d'application
Immunohistochemistry: 1:50-1:100 Immunofluorescence: 1:100-1:200
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Détails sur VEGFR2/CD309
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Antigène
VEGFR2/CD309 (VEGFR2)
(VEGF Receptor 2 (VEGFR2))
Autre désignation
VEGFR2 (VEGFR2 Produits )
Synonymes
anticorps CD309, anticorps FLK1, anticorps VEGFR, anticorps VEGFR2, anticorps 6130401C07, anticorps Flk-1, anticorps Flk1, anticorps Krd-1, anticorps Ly73, anticorps VEGFR-2, anticorps sVEGFR-2, anticorps Vegfr-2, anticorps FLK-1, anticorps flk-1, anticorps vegfr-2, anticorps KDR, anticorps FLK/KDR, anticorps flk1, anticorps flk1b, anticorps kdrb, anticorps si:busm1-205d10.1, anticorps si:ch211-254j6.1, anticorps si:ch211-278f21.4, anticorps wu:fc31a09, anticorps fk52c05, anticorps flk, anticorps kdr, anticorps kdra, anticorps vegfr2, anticorps vegfr4, anticorps vegr2, anticorps wu:fk52c05, anticorps kinase insert domain receptor, anticorps kinase insert domain protein receptor, anticorps vascular endothelial growth factor receptor kdr-like, anticorps kinase insert domain receptor (a type III receptor tyrosine kinase), anticorps kinase insert domain receptor like, anticorps KDR, anticorps Kdr, anticorps LOC100136647, anticorps kdr, anticorps kdrl
Sujet
Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions
Poids moléculaire
230 kDa
NCBI Accession
NP_002244
UniProt
P35968
Pathways
Signalisation RTK , Glycosaminoglycan Metabolic Process , Signaling Events mediated by VEGFR1 and VEGFR2 , Growth Factor Binding , Regulation of long-term Neuronal Synaptic Plasticity , VEGF Signaling
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