RAC1 anticorps (pSer71)

N° du produit ABIN362231

L’anticorps anti-RAC1 Polyclonal Lapin est utilisé pour la détection de RAC1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour RAC1 anticorps (pSer71) (ABIN362231)

Antigène: RAC1

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAC1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RAC1 anticorps

Épitope: pSer71

Specificité: The antibody detects endogenous level of Rac1 only when phosphorylated at serine 71.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogène: Peptide sequence around phosphorylation site of pSer71 (P-L-S (p) -Y-P) derived from Human Rac1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotype: IgG

Information d'application

Indications d'application: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur RAC1

Antigène: RAC1

Sujet: Rac1 encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 28 kDa

NCBI Accession: NP_008839

UniProt: P63000

Pathways: Signalisation WNT, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling