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RPS6KB1 anticorps (pThr421)
RPS6KB1
Reactivité: Humain, Souris, Rat
WB, IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-RPS6KB1 anticorps
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Antigène
Voir toutes RPS6KB1 Anticorps
RPS6KB1
(Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
Épitope
Tous les épitopes à travers RPS6KB1 Anticorps.
pThr421
Reactivité
Toutes les réactivités sur RPS6KB1 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur RPS6KB1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur RPS6KB1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers RPS6KB1 Anticorps
Cet anticorp RPS6KB1 est non-conjugé
Application
Tous les applications à travers RPS6KB1 Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Specificité
The antibody detects endogenous level of p70 S6 Kinase only when phosphorylated at threonine 421.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Immunogène
Peptide sequence around phosphorylation site of pThr421 (P-R-T (p) -P-V) derived from Human p70 S6 Kinase. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
Isotype
IgG
Top Product
Discover our top product RPS6KB1 Anticorps primaire
Alternatives
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anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (pThr389), (pThr412) antibody
RPS6KB1
Reactivité: Humain, Souris, Rat, Porc
WB, IHC, ELISA, IF, ICC
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
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Indications d'application
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100 Immunofluorescence: 1:100-1:200
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Références pour anticorps anti-RPS6KB1 (ABIN362316)
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Tang, Zhou, Zhou : "Dauricine inhibits insulin-like growth factor-I-induced hypoxia inducible factor 1alpha protein accumulation and vascular endothelial growth factor expression in human breast cancer cells. " dans: Acta pharmacologica Sinica , Vol. 30 , Issue 5 , pp. 605-16 , (2009 ) (PubMed ).
Détails sur RPS6KB1
(cache)
Antigène
RPS6KB1
(Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
Autre désignation
p70 S6 Kinase (RPS6KB1 Produits )
Synonymes
anticorps PS6K, anticorps S6K, anticorps S6K-beta-1, anticorps S6K1, anticorps STK14A, anticorps p70 S6KA, anticorps p70(S6K)-alpha, anticorps p70-S6K, anticorps p70-alpha, anticorps 10539, anticorps 7084, anticorps CG10539, anticorps DS6K, anticorps Dmel\\CG10539, anticorps Dp70S6k, anticorps Dp70[s6k], anticorps Dp70s6k, anticorps S6k, anticorps dS6K, anticorps dS6k, anticorps dp70[S6k], anticorps dp70s6k, anticorps dps6k, anticorps ds6k, anticorps fs(3)07084, anticorps l(3)07084, anticorps p70 S6K, anticorps p70/S6K, anticorps p70S6K, anticorps p70[S6 kinase], anticorps p70[S6K], anticorps p70[S6k], anticorps p70[S6kinase], anticorps p70s6K, anticorps s6k, anticorps s6k11, anticorps 2610318I15Rik, anticorps 4732464A07Rik, anticorps 70kDa, anticorps AA959758, anticorps AI256796, anticorps AI314060, anticorps p70/85s6k, anticorps p70s6k, anticorps p70s6k-A, anticorps p70-s6k, anticorps ps6k, anticorps rps6kb1, anticorps rps6kb1-A, anticorps s6K1, anticorps stk14a, anticorps fc51h01, anticorps wu:fc51h01, anticorps zgc:55713, anticorps ribosomal protein S6 kinase B1, anticorps Ribosomal protein S6 kinase, anticorps ribosomal protein S6 kinase, polypeptide 1, anticorps ribosomal protein S6 kinase B1 L homeolog, anticorps ribosomal protein S6 kinase B1 S homeolog, anticorps ribosomal protein S6 kinase b, polypeptide 1b, anticorps RPS6KB1, anticorps S6k, anticorps Rps6kb1, anticorps rps6kb1.L, anticorps rps6kb1.S, anticorps rps6kb1b
Sujet
Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.
Poids moléculaire
85 kDa
NCBI Accession
NP_003152
UniProt
P23443
Pathways
Signalisation PI3K-Akt , Signalisation RTK , AMPK Signaling , Regulation of Cell Size , Skeletal Muscle Fiber Development , Feeding Behaviour , G-protein mediated Events , Smooth Muscle Cell Migration , Interaction of EGFR with phospholipase C-gamma , L'effet Warburg
Vus récemment
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