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SMAD2 anticorps (pSer467)
SMAD2
Reactivité: Humain, Souris, Rat
WB
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-SMAD2 anticorps
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Antigène
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SMAD2
(SMAD, Mothers Against DPP Homolog 2 (SMAD2))
Épitope
Tous les épitopes à travers SMAD2 Anticorps.
pSer467
Reactivité
Toutes les réactivités sur SMAD2 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur SMAD2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur SMAD2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers SMAD2 Anticorps
Cet anticorp SMAD2 est non-conjugé
Application
Tous les applications à travers SMAD2 Anticorps.
Western Blotting (WB)
Specificité
The antibody detects endogenous level of Smad2 only when phosphorylated at serine 467.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Immunogène
Peptide sequence around phosphorylation site of pSer467 (C-S-S-M-S (p) ) derived from Human Smad2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
Isotype
IgG
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Information d'application
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Indications d'application
Western blotting: 1:500-1:1000
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Références pour anticorps anti-SMAD2 (ABIN362416)
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Zhang, Shen, Zhang, Wan, Yao, Wu, Wang, Chen, Yan, Jiang : "Induction of thoracic aortic remodeling by endothelial-specific deletion of microRNA-21 in mice. " dans: PLoS ONE , Vol. 8 , Issue 3 , pp. e59002 , (2013 ) (PubMed ).
Détails sur SMAD2
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Antigène
SMAD2
(SMAD, Mothers Against DPP Homolog 2 (SMAD2))
Autre désignation
Smad2 (SMAD2 Produits )
Synonymes
anticorps JV18, anticorps JV18-1, anticorps MADH2, anticorps MADR2, anticorps hMAD-2, anticorps hSMAD2, anticorps jv18, anticorps Xmad2, anticorps madh2, anticorps madr2, anticorps XSmad2, anticorps hmad-2, anticorps hsmad2, anticorps jv18-1, anticorps smad-2, anticorps fj43c06, anticorps wu:fj43c06, anticorps 7120426M23Rik, anticorps Madh2, anticorps Madr2, anticorps Smad-2, anticorps mMad2, anticorps MAD homolog 2, anticorps Mothers against DPP homolog 2, anticorps SMAD 2, anticorps Smad2, anticorps SMAD family member 2, anticorps SMAD family member 2-Z, anticorps SMAD family member 2 S homeolog, anticorps SMAD2, anticorps SMAD2Z, anticorps smad2, anticorps smad2.S, anticorps Smad2
Sujet
Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.
Poids moléculaire
60 kDa
UniProt
Q15796
Pathways
Cycle Cellulaire , Hormone Transport , Chromatin Binding , Protein targeting to Nucleus
Vus récemment
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