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CDKN1B anticorps (AA 8-12)
CDKN1B
Reactivité: Humain, Souris, Rat
WB, IHC
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-CDKN1B anticorps
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Antigène
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CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
Épitope
Tous les épitopes à travers CDKN1B Anticorps.
AA 8-12
Reactivité
Toutes les réactivités sur CDKN1B Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur CDKN1B Anticorps
Lapin
Clonalité
Toutes les clonalités sur CDKN1B Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CDKN1B Anticorps
Cet anticorp CDKN1B est non-conjugé
Application
Tous les applications à travers CDKN1B Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC)
Specificité
The antibody detects endogenous level of total p27Kip1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogène
Peptide sequence around AA 8-12 (N-G-S-P-S) derived from Human p27Kip1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype
IgG
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Information d'application
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Indications d'application
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Références pour anticorps anti-CDKN1B (ABIN362757)
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Yang, Xu, Li, Duan, Fu, Zhang, Zhao, Qiao, Chen, Geng, Che, Cao, Wang, Zhang, Long, He, Cui, Chen, Wang, Liu : "Cloning and characterization of a novel intracellular protein p48.2 that negatively regulates cell cycle progression. " dans: The international journal of biochemistry & cell biology , Vol. 41 , Issue 11 , pp. 2240-50 , (2009 ) (PubMed ).
Détails sur CDKN1B
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Antigène
CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
Autre désignation
p27Kip1 (CDKN1B Produits )
Synonymes
anticorps CDKN4, anticorps KIP1, anticorps MEN1B, anticorps MEN4, anticorps P27KIP1, anticorps cdkn1b, anticorps sb:cb611, anticorps wu:fb63g10, anticorps wu:fb64g10, anticorps wu:fe18e03, anticorps CDKN1B, anticorps Kip1, anticorps p27, anticorps FAM14D, anticorps ISG12, anticorps ISG12A, anticorps P27, anticorps Cdki1b, anticorps AA408329, anticorps AI843786, anticorps p27Kip1, anticorps cdkn1bl, anticorps cyclin dependent kinase inhibitor 1B, anticorps cyclin-dependent kinase inhibitor 1Bb, anticorps interferon alpha inducible protein 27, anticorps cyclin-dependent kinase inhibitor 1B, anticorps cyclin-dependent kinase inhibitor 1Ba, anticorps CDKN1B, anticorps cdkn1bb, anticorps IFI27, anticorps Cdkn1b, anticorps cdkn1ba
Sujet
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.
Poids moléculaire
27 kDa
NCBI Accession
NP_004055
UniProt
P46527
Pathways
Cycle Cellulaire , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Positive Regulation of Peptide Hormone Secretion , Negative Regulation of Hormone Secretion , Sensory Perception of Sound , Mitotic G1-G1/S Phases , DNA Replication , Positive Regulation of Endopeptidase Activity , Synthesis of DNA , Autophagy
Vus récemment
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