FOXO4 anticorps (AA 195-199)

N° du produit ABIN362777

Cet anticorps Lapin Polyclonal détecte spécifiquement FOXO4 dans WB et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour FOXO4 anticorps (AA 195-199) (ABIN362777)

Antigène: FOXO4 (Forkhead Box O4 (FOXO4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-FOXO4 anticorps

Épitope: AA 195-199

Specificité: The antibody detects endogenous level of total AFX protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Immunogène: Peptide sequence around AA 195-199 (A-A-S-M-D) derived from Human AFX. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype: IgG

Information d'application

Indications d'application: Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur FOXO4

Antigène: FOXO4 (Forkhead Box O4 (FOXO4))

Autre désignation: AFX

Sujet: Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.

Poids moléculaire: 65 kDa

NCBI Accession: NP_001164

UniProt: P98177

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation