ARNT anticorps

N° du produit ABIN363326

L’anticorps anti-ARNT Polyclonal produit chez le Lapin a été validé pour WB, IHC, IP et ChIP. Il convient pour la détection de ARNT dans des échantillons provenant de Humain, Souris, Rat, Boeuf (Vache), Mouton et Furet. }

Aperçu rapide pour ARNT anticorps (ABIN363326)

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Mouton, Furet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARNT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-ARNT anticorps

Specificité: Reacts with human HIF 1 beta /ARNT

Réactivité croisée: Souris, Boeuf (Vache), Mouton, Rat (Rattus)

Réactivité croisée (Details): Cross reacts with proteins from bovine, sheep, mouse, rat and ferret. Not tested in other species.

Purification: Antiserum

Immunogène: Fusion protein to human HIF-1 beta

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
ChIP1:10-1:500 ICC/IF (Negative), IHC1:150, IP1:10-1:500, WB1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: , Sodium azide 0.02 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C/-80 °C

Stockage commentaire: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Détails sur ARNT

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Autre désignation: Hypoxia-Inducible Factor 1-beta

Sujet: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

ID gène: 405

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, L'effet Warburg